Isotopically Labeled Compounds
Medchemexpress LLC Rabeprazole-d4 sodium | 117976-90-6 | 98.6% | 5 MG
Rabeprazole-d4 (sodium) is the deuterium labeled Rabeprazole sodium, a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. It induces apoptosis and acts as a uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. This compound can be used for the research of gastric ulcerations and gastroesophageal reflux.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes, potentially affecting pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC O-Toluic acid-13C | 70838-82-3 | 99% | 137.14 | 100 MG
o-Toluic acid-13C is the 13C labeled o-Toluic acid, which is a benzoic acid substituted by a methyl group at position 2. It functions as a xenobiotic metabolite and is intended for research use only. This compound is valuable as a tracer and an internal standard in quantitative analysis.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Balsalazide-d4 | 2714315-25-8 | 99.9% | 1 MG
Balsalazide-d4 is a deuterium-labeled form of Balsalazide. It can be used as a tracer and as an internal standard for quantitative analysis. Deuterium substitution can influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Suppresses colitis-associated carcinogenesis through modulation of the IL-6/STAT3 pathway
Medchemexpress LLC Deruxtecan-d5 | 00-00-0 | 98.4% | C52H51D5FN9O13 | 10MG
Deruxtecan-d5 is a deuterium-labeled derivative of deruxtecan supplied as an off-white to light yellow solid for use as a tracer or internal standard in quantitative analysis (NMR, GC-MS, LC-MS) and antibody-drug conjugate research. It is highly pure, readily soluble in DMSO, and should be stored cold and protected from moisture and light.
- deuterium-labeled internal standard for quantitative assays.
- high purity: 98.4%.
- solid form, off-white to light yellow.
- soluble in DMSO ≥ 100 mg/mL.
- storage: -20°C; in solvent -80°C for 6 months, -20°C for 1 month.
- suitable for tracer studies and ADC research.
Medchemexpress LLC Sertindole-d4 | 1794737-42-0 | 98.6% | C24H22D4ClFN4O | 10MG
Sertindole-d4 is the deuterium-labeled analogue of sertindole supplied as a stable-isotope internal standard for analytical workflows. Provided as a sealed powder with high purity and defined storage conditions, it supports accurate quantitation, ADME studies, and metabolite identification by LC-MS.
- Deuterium-labeled analogue for use as an internal standard.
- High purity suitable for analytical applications.
- Suitable for LC-MS quantitation and metabolite identification.
- Provided as a sealed powder for stable storage.
- Specific storage recommendations for long-term stability.
Medchemexpress LLC Nadolol-d9 | 94513-92-5 | MFCD00049405 | 97.0% | 5 MG
Nadolol-d9 is a deuterium labeled Nadolol, functioning as a non-selective and orally active β-adrenergic receptors blocker. It is intended for research use only.
- Used as a tracer
- Functions as an internal standard for quantitative analysis
- Supports NMR, GC-MS, or LC-MS applications
Cayman Chemical EtIfoxIn-13C-d3 500ug
An internal standard for the quantification of etifoxine by GC- or LC-MS
Cayman Chemical Fluprostenol-d4 500ug
An internal standard for the quantification of fluprostenol by GC- or LC-MS
Medchemexpress LLC Bupivacaine-d9 | 474668-57-0 | MFCD11977968 | 99.0% | 1 MG
Bupivacaine-d9 is a deuterium-labeled Bupivacaine, functioning as an NMDA receptor inhibitor. It effectively blocks sodium, L-calcium, and potassium channels and can be utilized in chronic pain research.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Trospium-d8 chloride | 10405-02-4 | 1 MG
Trospium-d8 (chloride) is the deuterium-labeled form of Trospium chloride. Trospium chloride is an orally active, specific, and competitive antagonist of muscarinic cholinergic receptors (mAChRs), exhibiting antimuscarinic activity. It binds with high affinity to muscarinic receptors M1, M2, and M3, but not nicotinic cholinergic receptors.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporation of stable heavy isotopes can affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Cabozantinib-d6 | 1802168-46-2 | 98.1% | 50 MG
Cabozantinib-d6 is the deuterium labeled Cabozantinib. Cabozantinib is a potent multiple receptor tyrosine kinases (RTKs) inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50s of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have been incorporated into drug molecules for quantitation during drug development.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC (Rac)-Cotinine-d3 | 110952-70-0 | 99.9% | 5 MG
(Rac)-Cotinine-d3 is the deuterium-labeled version of (Rac)-Cotinine. It is intended for research use only. The incorporation of stable heavy isotopes such as deuterium into drug molecules can serve as tracers for quantitative analysis during drug development, and has also been noted for its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC (Rac)-Cotinine-d3 | 110952-70-0 | 99.9% | 50 MG
(Rac)-Cotinine-d3 is the deuterium labeled (Rac)-Cotinine. Deuteration has gained attention due to its potential to impact the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes incorporated into drug molecules.
- Potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Nad+-13c5 ammonium | 53-84-9 | 98.9% | 1 MG
NAD+-13C5 (ammonium) is a 13C labeled NAD+ compound intended for research use only. This compound can be utilized as a tracer or as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS. Stable heavy isotopes are incorporated into drug molecules primarily as tracers for quantitation during drug development. Shipping is at room temperature in the continental US, with variations elsewhere. Solid storage requires -20°C, sealed, away from moisture and light. If in solvent, store at -80°C for 6 months or -20°C for 1 month, also sealed and away from moisture and light.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Ethambutol-d4 | 1129526-19-7 | 98.1% | 1 MG
Ethambutol-d4 is a deuterium-labeled version of Ethambutol, a bacteriostatic antimycobacterial agent. It functions by inhibiting arabinosyl transferases, thereby obstructing the formation of bacterial cell walls. This compound can be utilized as a tracer and as an internal standard for quantitative analysis in various methods.
- Deuterium-labeled ethambutol
- Bacteriostatic antimycobacterial agent
- Inhibits arabinosyl transferases
- Obstructs bacterial cell wall formation
- Suitable for use as a tracer
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS